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ReMind a phytochemical composition specially developed by Danor to improve cognitive deficits and to ameliorate general and age related declined ability to remember.

Each ReMind capsule contains 60 mg of standardized leaf extract of Ginkgo Biloba that includes minimum 14 mg of Ginkgo Biloba flavone glycosides; 200 mg of phosphatidylcholine enriched soy phospholipids (phosphatidylcholine enriched soy lecithin) that includes minimum 60 mg phosphatidylcholine, 12 mg phosphatidylethanolamine and 18 mg phosphtidylinositol; and 40 mg of l-serine.

All these ReMind components are important and act together and synergetic ally to restore age-related memory loss and improve concentration and learning.
Ginkgo Biloba leaves extract is important to alleviate symptoms associated with cognitive deficits, e.g., decreased memory performance, lack of concentration, decreased alertness and dizziness. Pharmacological studies have shown that the therapeutic effect of Ginkgo is based on several active constituents with vasoactive and free radical-scavenging properties. The use of Ginkgo extract in either dementia of the Alzheimer or multi-infarct type or i n the case of cerebral insufficiency, a symptom complex related to age-dependent impairment of cerebral circulation, is based on positive results from good-quality placebo-controlled studies over the past 50 years. Where Ginko Biloba leaves extract was employed to restore mental acuity, to increase blood flow to the brain, improving alertness and concentration as well as a treatment for hearing, vision and other problems associated with inadequate blood circulation.

Phospholipid components (Lecithins) are brain nutrients naturally found in the brain and in all cell membranes. They are vital to normal brain function. In aging, the amount required appears to increase and need to be supplemented. The role of the phospholipid phosphatidylserine that is derived in the body from phospholipids such as phosphatidylcholine and phosphatidylethanolamine in the presence of ample l-serine is highly important to restore age related memory loss and reverse aggravated old age cognitive decline.

L-Serine and some of its derivatives (e.g., ethanolamine, phosphatidylserine, etc.) have important role well established in biological membranes. Although belonging to the group of non-essential amino acids l-serine have been shown to exhibit specific actions in the nervous system. L-serine promotes the survival of cerebrocortical neurons in a concentration-dependent manner, acting much like as a neurotra-nsmitter. L-serine is an important factor for the morphological differentiation of neurons.

   Some related references:

1. Soholm B. Clinical improvement of memory and other cognitive functions by Ginkgo biloba: review of relevant literature. Adv Ther. 1998 Jan-Feb; 15(1):54-65. 2. Warburton DM. Ginkgo biloba extract and cognitive decline. Br J Clin Pharmacol. 1993 Aug;36(2):137. 3. Wincor MZ. Ginkgo biloba for dementia: a reasonable alternative? J Am Pharm Assoc (Wash). 1999 May-Jun;39(3):415-6. 4. Logani S, Chen MC, Tran T, Le T, Raffa RB. Actions of Ginkgo Biloba related to potential utility for the treatment of conditions involving cerebral hypoxia. Life Sci. 2000 Aug 11;67(12):1389-96. Review. 5. Holgers KM, Axelsson A, Pringle I. Ginkgo biloba extract for the treatment of tinnitus. Audiology. 1994 Mar-Apr;33(2):85-92. 6. Hopfenmuller W. Evidence for a therapeutic effect of Ginkgo biloba special extract. Meta-analysis of 11 clinical studies in patients with cerebrovascular insufficiency in old age]. Arzneimittelforschung. 1994 Sep;44(9):1005-13. 6. Curtis-Prior P, Vere D, Fray P. Therapeutic value of Ginkgo biloba in reducing symptoms of decline in mental function. J Pharm Pharmacol. 1999 May;51(5):535-41. 7. Lugasi A, Horvahovich P, Dworschak E. Additional information to the in vitro antioxidant activity of Ginkgo biloba L. Phytother Res. 1999 Mar;13(2):160-2. 8. Maurer K, Ihl R, Dierks T, Frolich L. Clinical efficacy of Ginkgo biloba special extract EGb 761 in dementia of the Alzheimer type. J Psychiatr Res. 1997 Nov-Dec;31(6):645-55. 9. Clostre F. Ginkgo biloba extract (EGb 761). State of knowledge in the dawn of the year 2000. Ann Pharm Fr. 1999 Jul;57 Suppl 1:1S8-88. Review. 10. Wesnes KA, Faleni RA, Hefting NR, Hoogsteen G, Houben JJ, Jenkins E, Jonkman JH, Leonard J, Petrini O, van Lier JJ. The cognitive, subjective, and physical effects of a ginkgo biloba/panax ginseng combination in healthy volunteers with neurasthenic complaints. Psychopharmacol Bull. 1997;33(4):677-83. 12. Mack RB. Non-remembrance of things past. Ginkgo biloba for memory loss. N C Med J. 2000 Jan-Feb;61(1):393-5.. 13. Kanowski S, Herrmann WM, Stephan K, Wierich W, Horr R. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry. 1996 Mar;29(2):47-56. 14. Smith PF, Maclennan K, Darlington CL. The neuroprotective properties of the Ginkgo Biloba leaf: a review of the possible relationship to platelet-activating factor (PAF). J Ethnopharmacol. 1996 Mar;50(3):131-9. Review. 15. Rai GS, Shovlin C, Wesnes KA. A double-blind, placebo controlled study of Ginkgo biloba extract ('tanakan') in elderly outpatients with mild to moderate memory impairment. Curr Med Res Opin. 1991;12(6):350-5. 16. Jacobs BP, Browner WS. Ginkgo biloba: a living fossil. Am J Med. 2000 Mar;108(4):341-2. 17. Kennedy DO, Scholey AB, Wesnes KA. The dose-dependent cognitive effects of acute administration of Ginkgo biloba to healthy young volunteers. Psychopharmacology (Berl). 2000 Sep;151(4):416-23. 18. Le Bars PL, Kieser M, Itil KZ. A 26-week analysis of a double-blind, placebo-controlled trial of the ginkgo biloba extract EGb 761 in dementia. Dement Geriatr Cogn Disord. 2000 Jul-Aug;11(4):230-7.20: 19. Yang L, Zhang B, Toku K, Maeda N, Sakanaka M, Tanaka J.,Improvement of the viability of cultured rat neurons by the non-essential amino acids L-serine and glycine that upregulates expression of the anti-apoptotic gene product Bcl-w. Neurosci Lett. 2000 Dec 8;295(3):97-100. 20. Middleton G, Wyatt S, Ninkina N, Davies AM. Reciprocal developmental changes in the roles of Bcl-w and Bcl-x(L) in regulating sensory neuron survival. Development. 2001;128(3):447-457. 21. Furuya S, Tabata T, Mitoma J, Yamada K, Yamasaki M, Makino A, Yamamoto T, Watanabe M, Kano M, Hirabayashi Y. L-serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11528-33. 22. Mitoma J, Furuya S, Hirabayashi Y. A novel metabolic communication between neurons and astrocytes: non-essential amino acid L-serine released from astrocytes is essential for developing hippocampal neurons. Neurosci Res. 1998 Feb;30(2):195-9. 23. Hamner S, Arumae U, Li-Ying Y, Sun YF, Saarma M, Lindholm D. Functional Characterization of Two Splice Variants of Rat Bad and Their Interaction with Bcl-w in Sympathetic Neurons. Mol Cell Neurosci. 2001 Jan;17(1):97-106. 24. Hamner S, Skoglosa Y, Lindholm D. Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system. Neuroscience. 1999;91(2):673-84. 25. Mitoma J, Furuya S, Hirabayashi Y. A novel metabolic interaction between neurons and glial cells through L-serine: an essential role for astroglia-derived L-serine in the survival and development of CNS neurons. Seikagaku. 1999 Jul;71(7):536-41. Review., Neurosci Lett. 2000 Feb 4;279(3):193-5. 26. Savoca R, Ziegler U, Sonderegger P. Effects of L-serine on neurons in vitro. J Neurosci Methods. 1995 Sep-Oct;61(1-2):159-67. 27. Alvarez XA, Mouzo R, Pichel V, Perez P, Laredo M, Fernandez-Novoa L, Corzo L, Zas R, Alcaraz M, Secades JJ, Lozano R, Cacabelos R. Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion. Methods Find Exp Clin Pharmacol. 1999 Nov;21(9):633-44. 28. Pepping J. Phosphatidylserine. Am J Health Syst Pharm. 1999 Oct 15;56(20):2038, 2043-4. Review.. 29. Pepeu G. The phosphatidylserine story. Nutrition. 1999 Oct;15(10):789. 30. Blokland A, Honig W, Brouns F, Jolles J. 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