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AlternaForte is a soy phytochemical composition with added Black cohosh
specially developed by Danor for the prevention and amelioration of severe
problems associated with menopausal syndromes, osteoporosis and other maladies
as a natural alternative to Hormone (Estrogen) Replacement Therapy (HRT).
AlternaForte is specially designed product formulated to
help the difficult unpleasant symptoms occurring in severe cases of hot
flashes.
Each AlternaForte capsule contain soy phytochemicals extract
that provide 25 mg of soy isoflavones, plant food material that act naturally
both as estrogens and estrogen antagonists.
AlternaForte capsule also contain 60 mg of Black Cohosh
(Cimicifuga racemosa) that give extra added protection against menopausal
problems occurring in severe cases of hot flashes.
AlternaForte in contrast to most "isoflavones" and "phytoestrogens"
pills or tablets available in the market place is composed not only of a
desired amount of isoflavones but contains all the other highly beneficial
phytochemicals of the soybean as well as effective amount of Black Cohosh.
AlternaForte is in essence a natural food product made
from an aqueous alcoholic extract of the soybean as well as Black Cohosh.
This soy extract is a natural and very highly concentrated extract of all
the soy phytochemicals in the same form and quality as present in the original
soybean with the exception that it does not contain the soy storage proteins,
oil and fiber.
AlternaForte comprises of soy constituents that are considered
extremely beneficial for the maintenance of good health and of Black Cohosh.
Black cohosh is a safe and effective alternative to estrogen showing good
therapeutic efficacy for menopausal symptoms (e.g., hot flashes, profuse
sweating, sleep disturbances, depressive moods) and tolerability profiles.
AlternaForte also contains soy sugars, of which about half
are the Bifidobacteria growth promoting oligosugars: stachyose and raffinose.
These oligosugars serve as carrier of the above mentioned soy phytochemical
constituents.
AlternaForte components are very useful to prevent and aid menopausal
syndromes especially severe hot flashes, osteoporosis, hip fractures, breast,
colon, lung, and other divers types of carcinogenesis, heart diseases, etc.
AlternaForte components carry antioxidants that have cholesterol-lowering
effects and boost the immune system. The benign effects of the combining
constituents of the phytochemicals for the prevention and amelioration of
various diverse pathological conditions are well documented in the literature.

The soy phytochemicals - Saponins, Bowman-Birk trypsin and chymotrypsin
inhibitor (BBI), phytates and phenolic acids constituents of AlternaForte
are considered as having a prime responsibility for the anticancer properties
alongside with the isoflavones. The combined soy phytochemicals in AlternaForte
have apparently a very favorable synergetic effect, acting as estrogen
antagonists and as anti-androgens, reducing the proliferation of cells
and having anti-oxidant, anti-microbial, anti-fungus and anti-viral activities.
The soy phytochemicals are apparently able to block inflammatory responses,
act as signal interceptor and thus able to meliorate conditions resulting
from aberrations in signaling pathways. Phytoestrogens are compounds from
vegetal sources, similar in their biological activity to estrogen. One
of the main groups of phytoestrogens is the soy isoflavones group, containing
Genistein and Daidzein, which can be found mostly in soy and its products.
Black Cohosh contains different isoflavones that act extremely well synergistically
with the soy phytoestrogens to prevent extreme phenomenon of hot flashes.
In European phytotherapy, it is commonly prescribed as an effective alternative
to hormone replacement therapy for menopausal syndromes. documented in
the literature.
Some related references:
1. Brzezinski A, et al. Short-term effects of phytoestrogen-rich diet on postmenopausal women, Menopause The Journal of the North American Menopausal Society, 1997 4:89-94.
2. Hardy ML., Herbs of special interest to women, J Am Pharm Assoc (Wash). 2000 Mar-Apr;40(2):234-42; quiz 327-9.
3. Janezic S, et al. Role of dietary phytosterol in colon carcinogenesis. Proc 34 Ann Meet Can Fed Biol Soc Kingston, Onterio, 1991.
4. Koo M, et al. Long-term effects of bifidobacteria and neosugar on precursor lesions of colonic cancer in CF1 mice. Nutr. Cancer, 1991 16:249.
5. Lieberman S., A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause, J Women’s Health. 1998 Jun;7(5):525-9.
6. Liske E., Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders, Adv Ther. 1998 Jan-Feb; 15(1):45-53.
7. Matson F, et al. Effects of plant sterol esters on the absorption of dietary cholesterol. J Nutr, 1977 107:1139-1146.
8. Messadi D, et al., Inhibition of carcinogenesis by a protease inhibitor. 1986.JNCI 76:447-452
9. McKenna DJ, Jones K, Humphrey S, Hughes K., Black cohosh: efficacy, safety, and use in clinical and preclinical applications, Altern Ther Health Med. 2001 May-Jun;7(3):93-100
10. Morelli V, Naquin C., Alternative therapies for traditional disease states: menopause. Am Fam Physician, 2002 Jul 1;66(1):129-34.
11. Murkies AL. Et al. Phytoestrogens. J Clin Endocrin Metab, 1998. 83:297-303.
12. Newmark H, et al. Plant phenolics as mutational and precarcinogenic events. Can J Physiol Pharmacol 65:461-466,1987. 7.
13. Potter SM, et al. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am J Clin. Nutr. 68 (6 suppl.) 1375S-1379S 1998 Roa A and Sumg M., Saponins as anticarcinogens. J Nutr ,1995 125:771-724.
14. Swaminathan R. Nutritional factors in osteoporosis. Int J Clin Pract, 1999 53(7):540-548
15. Thompson L, et al., Phytic acid and minerals: effect on early markers of risk for mammary and colon carcinogenesis. Carcinogenesis, 1991 12:2041-2045.

Introduction
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